A young woman with this soft asymptomatic plaque on the right thigh since birth.
The nevus lipomatosus superficialis (NLS) is an uncommon congenital (or acquired in the first 3 decades) grouping of soft, fleshy nodules, usually of the buttocks or thighs. It represents thinning of the dermis with protrusion of fat.
The first type is the classical type, which is characterized by multiple flesh-colored or yellowish sessile lesions with a tendency to coalesce into plaques. They usually have a smooth or corrugated surface and zonal distribution following natural cleavage lines of the skin has been reported. They have a predilection for the pelvic girdle, lumbar, and sacral regions, including posterior upper thighs. They can be sessile or pedunculated.
The second type comprises a solitary, domed, or sessile lesion and has been reported at sites other than the lower trunk such as the knee, axilla, arm, and ear. It is also referred to as a a pedunculated lipofibroma.
No treatment is needed. Simple excision may be done.
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