FOX FORDYCE DISEASE
Fox-Fordyce disease (FFD) is an uncommon chronic follicular-based papular dermatosis confined to apocrine gland-bearing skin. It is caused by keratin plugging of the follicular infundibulum at the distal portion of the apocrine sweat duct and less often by plugging of apoeccrine ducts. This obstruction causes apocrine sweat retention and, over time, rupture of glands with secondary inflammation.
- Laser hair removal has been reported to precipitate FFD.
- Most patients are women 13-35 years of age.
Clinical
Uniformly distributed, pruritic, flesh-colored papules in the axilla, areola, groin, and perineum are characteristic. Partial alopecia is typical. Itching is common. Women at puberty or after are typically affected with men developing lesions only one-tenth as often. Four cases of FFD subsequent to laser hair removal have been described.
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