A 5-year-old with 2 days of fever, headache, a runny nose and then "slapped cheeks".
Then 2 days later, this lacey rash on the trunk and limbs.
Erythema infectiosum (EI), also known as fifth disease, is caused by Parvovirus B19. The typical patient is a young child who develops flu-like symptoms, then inflamed, bilateral ("slapped") cheeks, then lace-like reticulate erythema of the trunk and extremities.
A prodrome of low-grade fever, headache, and mild cold-like symptoms (e.g., a stuffy or runny nose) occurs. An upset stomach (nausea and diarrhea) may occur. Approximately 2 days later, the "slapped cheek" rash appears. Then 1 to 3 days later, a red, lace-like rash appears, first on the torso and arms, and then on the rest of the body. It can be quite itchy.
There is no specific treatment as EI typically clears on its own. Treatment focuses on managing symptoms and providing comfort (rest, fluids, Tylenol etc.,).
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