CONGENITAL DERMAL MELANOCYTOSIS

Congenital Dermal Melanocytosis (CDM and formerly called Mongolian spot) is a congenital blue patch caused by the presences of dermal melanocytes. A related condition is acquired dermal melanocytosis.

Clinical

A congenital blue-black patch on the sacrum of an infant with darker skin is most characteristic. Caucasians may also be affected. In a large study of babies in India with CDM, more than 40% of CDM disappeared by 1 year. Multiple patches, extrasacral position, size larger than 10 cm, and dark-colored lesions were markers of persistence beyond 1 year

Lysosomal Storage Diseases

Dermal melanocytosis, particularly when extensive, is associated with both Hunter and Hurler syndromes, which are classified as lysosomal storage diseases (LSDs).

Treatment

The lesion usually fades by puberty. It may persist however, into adulthood. For those, laser treatment has been employed.

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