By Gary M. White, MD

Plane Xanthomas

Plane xanthomas (PX) are diffuse, planar, yellow discolorations of the skin caused by deposition of xanthomatous cells.


Large yellow patches or very slightly elevated plaques are characteristic. In one patient, normolipemic plane xanthomas occurred in a perifollicular distribution [Dermatology 1999;199;97].


Lab tests should include lipid profile, SPEP and other tests to exclude multiple myeloma. Plane xanthomas can precede the appearance of an underlying disease by several years, so careful followup and periodic laboratory examinations are recommended even for patients that seem to have no associated disorder. One report successfully treated PX of the face with 1,444-nm neodymium-doped yttrium aluminium garnet (Nd:YAG) laser [Ann Dermatol. 2015 Dec; 27(6): 769–770].


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