By Gary M. White, MD

Xanthoma Striatum Palmare Photo courtesy Stephen H. Ducatman MD

Xanthoma striatum palmare (XSP) or palmar crease xanthomas is a type of plane xanthoma and presents as yellow palmar creases. It usually occurs in type III (broad beta) hyperlipidemia.


The palmar creases appear yellow.


Evaluation and treatment of the hyperlipidemia by a specialist is appropriate. Specifically, patients may need apolipoprotein (apoE) genotyping, lipid profiling, documentation of dysbetalipoproteinemia by ultracentrifugation or nuclear magnetic resonance lipid profiling.

Additional Pictures

Photo courtesy Stephen H. Ducatman MD
Xanthoma Striatum Palmare


JAMA Derm 2016;152;1275


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