By Gary M. White, MD

Vilanova disease

Vilanova disease is a variant of erythema nodosum in which a solitary inflammatory plaque appears about the lower leg.


A painless, erythematous nodule enlarging to a plaque on the lower aspect of one shin in a woman is characteristic of Vilanova disease, also called subacute nodular migratory panniculitis. The lesion may be chronic with slow expansion. Arthralgias, an elevated ASO titer, and an elevated ESR frequently occur. Hypothyroidism has been associated. The lesion may be confused with cellulitis.


Oral potassium iodide is quite effective. IL triamcinolone may be tried for individual small lesions. An NSAID, e.g. indomethacin, may be helpful for the pain and may even clear the lesion [Adv Biomed Res. 2014 Dec 31;3:264]. See erythema nodosum for more treatment suggestions.

Additional Pictures

Vilanova disease Vilanova disease


Homepage | FAQs | Use of Images | Contact Dr. White

It is not the intention of to provide specific medical advice, diagnosis or treatment. only intends to provide users with information regarding various medical conditions for educational purposes and will not provide specific medical advice. Information on is not intended as a substitute for seeking medical treatment and you should always seek the advice of a qualified healthcare provider for diagnosis and for answers to your individual questions. Information contained on should never cause you to disregard professional medical advice or delay seeking treatment. If you live in the United States and believe you are having a medical emergency call 911 immediately.