By Gary M. White, MD
Vilanova disease is a variant of erythema nodosum in which a solitary inflammatory plaque appears about the lower leg.
- The term erythema nodosum migrans is often used.
- Occasionally, this and lipodermatosclerosis are confused.
A painless, erythematous nodule enlarging to a plaque on the lower aspect of one shin in a woman is characteristic of Vilanova disease, also called subacute nodular migratory panniculitis. The lesion may be chronic with slow expansion. Arthralgias, an elevated ASO titer, and an elevated ESR frequently occur. Hypothyroidism has been associated. The lesion may be confused with cellulitis.
Oral potassium iodide is quite effective. IL triamcinolone may be tried for individual small lesions. An NSAID, e.g. indomethacin, may be helpful for the pain and may even clear the lesion [Adv Biomed Res. 2014 Dec 31;3:264]. See erythema nodosum for more treatment suggestions.
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