By Gary M. White, MD
Vibratory angioedema is a physical urticaria in which itchy erythema and swelling occurs at the site of skin exposed to vibration.
- Running, motorcycling, electric lawnmower or pneumatic drill are typical stimuli.
- Swelling of the lips in musicians (e.g. horn, trumpet, saxaphonist) may occur.
- It may rarely occur as an autosomal dominant trait.
The standard approach with oral antihistamines should be tried. Dapsone, cyclosporine, methotrexate, and prednisone may be tried. Ketotifen worked well in one patient [CED 2012;38;151-3]. Amitriptyline and bromazepam helped a horn player [Dermatol Ther. 2014 Nov-Dec;27(6):361-4].
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