By Gary M. White, MD

Progressive vaccinia, also known as Vaccinia gangrenosum and Vaccinia necrosum Photograph courtesy Michal O. Murphy, MD

Progressive vaccinia (also known as "Vaccinia gangrenosum," and "Vaccinia necrosum") is a rare cutaneous condition caused by the vaccinia virus, characterized by painless, but progressive, necrosis and ulceration.


Sycosis Vaccinatum. A man who had been in close physical contact someone who had received the smallpox vaccination. JAMA Derm 2015;151;799.


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