TYPE 1 REVERSAL REACTION OF LEPROSY
By Gary M. White, MD
Type 1 reversal reaction is the inflammation of existing lesions of Leprosy and the development of new ones when there is improvement in cellular immunity. It may for example occur in HIV positive patients started on HAART. The condition is also called immune reconstitution inflammatory syndrome. It is most likely to occur in patients with borderline leprosy.
- May have edema of face, hands and feet.
- Nerve damage may occur.
- Treated with multi drug therapy (if not already on it) and oral steroids.
Hansen's disease in association with immune reconstitution inflammatory syndrome. Indian Dermatol Online J 2016;7:29-31
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