By Gary M. White, MD
Tripe palms is often a marker of pulmonary neoplasia. It is analogous to malignant acanthosis nigricans and may be associated with it. Clubbing may be seen as well. The most common neoplasia are from the gastrointestinal or respiratory tract. Tripe palms may occur before the malignancy is discovered or after.
Exaggeration of the normal dermatoglyphics on the palms is characteristic. The palmar skin takes on thickened and velvety appearance reminiscent of tripe (the rugose suface of the bovine forgut).
A workup of for an internal malignancy is the main, necessary intervention.
Dermatology Online Journal 18 (11)
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