By Gary M. White, MD

The Stewart Treves Syndrome (STS) is the development of an angiosarcoma in an area of chronic lymphedema.


Solitary or multiple red-blue papulonodules or plaques arising in an area of chronic lymphedema is characteristic.


Referral to a surgical oncologist is in order. Wide surgical excision or amputation appears to be the treatment of choice. Radiation therapy has also been used and less commonly chemotherapy.


An 81-year-old woman with a history of melanoma of the left calf, treated with a radical excision and unilateral inguinal lymph node dissection in 1992, presented with a 5-month history of an enlarging ulcerated plaque of coalescing purple papules and bruise-like nodules within a region of chronic lymphedema of the left lower limb. Dermatology Online Journal 18 (6)

A 86-year-old woman presented with a giant erythematous, edematous, purplish lobulated plaque on her right forearm anteromedially with a few satellite erythematous papulonodules on her arm. A small nodule had appeared 6 months ago on the forearm and grown rapidly. The patient had undergone a radical mastectomy operation 15 years ago due to right breast carcinoma and she has a diagnosis of chronic lymphoedema on her right arm for approximately 10 years. J Clin Diagn Res. 2016 Feb; 10(2)


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