SQUAMOUS CELL CARCINOMA OF THE LIP
Squamous cell carcinoma (SCC) accounts for the vast majority of all lip cancers with the lower lip representing almost all of these because of its exposure to the sun. See also squamous cell carcinoma and actinic cheilitis.
A slowly enlarging, hyperkeratotic papulonodule originating from the vermilion border of the lower lip is characteristic. SCC of the lip has a higher incidence of metastasis (from 3-20%) compared with cutaneous SCC.
Wedge resection is the preferred treatment. Mohs surgery is also highly effective for both primary and recurrent SCC and some have recommended it as the treatment of choice. Treatment of coexisting actinic cheilitis (e.g., with the CO2 laser) may lower the risk of local recurrence.
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