By Gary M. White, MD

segmental pigmentation disorder

The term "segmental pigmentation disorder" (SPD) is used to describe children with segmental and block-like hypo or hyperpigmentation with midline demarcation.


Onset is at birth or soon thereafter. About 3/4 of cases of SPD are hyperpigmented and about 1/4 are hypopigmented. The most common location is the torso, anteriorly. Lesions are segmental, but not dermatomal and do not follow the lines of Blaschko. Somatic mosaicism is thus postulated as the cause. Lesions may cross the midline by one or two centimeters. The lateral border is often less distinct than the medial.


The risk of systemic association is quite low and in fact, no reproducible pattern has as of yet been identified.


SPD usually fades over time, but may persist into adulthood. For hypopigmented lesions, any of the modalities employed for nevus depigmentosus or segmental vitiligo may be tried, e.g. the 308-nm laser.

Additional Pictures

SPD in an adult. Note the block-like shape, midline demarcation and the sharper border medially than laterally.
segmental pigmentation disorder segmental pigmentation disorder


DermatologĂ­a Argentina


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