by Gary White, MD
Rowell syndrome is when patients with lupus erythematosus develop lesions of erythema multiforme. It should be considered in patients with LE with EM-like lesions. It is still debated as to whether RS is an overlap syndrome, a real association, or coincidence of DLE and EM.
Major criteria (all three must be present):
- Diagnosis of SLE, DLE, or subacute cutaneous LE (SCLE)
- EM-like lesions (with or without mucosal involvement)
- ANA with a speckled pattern.
Minor criteria include (at least one):
- Anti-Ro/anti-La antibody
- Positive RF.
Azathioprine, antimalarials, prednisone, dapsone, and cyclosporine have been used with good results.
Dermatology Online Journal 15(8)
Dermatology Online Journal 14(3)
Indian Pediatrics 2012;49: 854-855
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