RHEUMATOID NEUTROPHILIC DERMATOSIS

By Gary M. White, MD


Rheumatoid neutrophilic dermatosis (RND) is a rare cutaneous manifestation of rheumatoid arthritis (RA). It usually occurs in those patients with severe RA and seems most common in middle-aged women. Histologically, it falls under the spectrum of neutrophilic vascular reactions. RND has also been reported in a patient with seronegative arthritis [JAAD 2001;45;596].

Clinical

Erythematous, urticarial papules and plaques on the trunk and extremities in a patient with rheumatoid arthritis is typical. The lesions tend to be symmetric and some lesions may take on a yellowish hue. The extensor aspects of the joints, dorsal hands, and arms are favored sites.

Treatment

Prednisone, dapsone, and cyclophosphamide have been used.

RegionalDerm

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