Reticular erythematous mucinosis (REM) is a benign accumulation of mucin in the dermis typically on the chest of a woman.
A reticulated, erythematous and infiltrated chronic eruption of the chest and back is characteristic of reticulated erythematous mucinosis. Middle-aged women are most commonly affected and the lesions are asymptomatic. A variant may present as an erythematous plaque on the chest called plaque-like cutaneous mucinosis. Sunlight has exacerbated the condition in some cases. The ANA should be negative. The similarities between REM and lupus erythematosus tumidus have made some suggest they are the same disease but others argue they are separate entities [J Eur Acad Dermatol Venereol Aug 2014]. One patient with a paraprotein has been reported.
Spontaneous resolution can occur. Hydroxychloroquine (e.g., 200-400/day) or another antimalarial is usually effective. Topical tacrolimus BID cleared one patient in 2 months. UVA1 radiation cleared one patient [AD 2004;140;660].
British Journal of Dermatology (2013) 169, pp1207–1211
Indian J Dermatol Venereol Leprol 2010;76:86
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