By Gary M. White, MD

Recurrent Cutaneous Eosinophilic Vasculitis (RCEV) is characterized by pruritic purpuric papules, annular urticarial plaques, and angioedema.


Clinically, one sees pruritic purpuric papules, annular urticarial plaques, and angioedema. Necrosis may occur.

Differential Diagnosis

Other considerations include hypereosinophilic syndrome (peripheral blood eosinophilia persisting for more than 6 months plus systemic involvement), Churg–Strauss vasculitis (bronchial asthma, peripheral blood eosinophilia, granulomas histologically) and Well's syndrome.


Systemic steroids are very helpful, but unfortunately, the disease is chronic and alternative treatments are desirable. Systemic tacrolimus, indomethacin, and suplatast tosilate have been used.


A 45-year-old woman presented with intensely pruritic, persistent red raised lesions over forearms, legs, palms, and soles of 5 years duration. Fever and constitutional symptoms were absent. Indian J Dermatol 2016;61:235

Diagn Pathol. 2013; 8: 185.


Homepage | FAQs | Contact Dr. White

It is not the intention of to provide specific medical advice, diagnosis or treatment. only intends to provide users with information regarding various medical conditions for educational purposes and will not provide specific medical advice. Information on is not intended as a substitute for seeking medical treatment and you should always seek the advice of a qualified healthcare provider for diagnosis and for answers to your individual questions. Information contained on should never cause you to disregard professional medical advice or delay seeking treatment. If you live in the United States and believe you are having a medical emergency call 911 immediately.