REACTIVE PERFORATING COLLAGENOSIS, FAMILIAL

By Gary M. White, MD


Reactive perforating collagenosis (RPC) is a rare inherited disease characterized by umbilicated, crusted papules at sites of trauma that histologically show extrusion of collagen through the epidermis. Onset is usually in childhood. Both AR, AD, and sporadic cases have been reported. DownÂ’s syndrome and Treacher Collins syndrome [JAAD 1996;35;982] have been associated. RPC is one of the perforating disorders.

Clinical

Umbilicated, crusted papules occur at sites of trauma.

Treatment

No good treatment is available other than avoiding trauma.

References

Indian J Dermatol Venereol Leprol 2014;80:86-7

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