WHITE (DE or HYPOPIGMENTED)

By Gary M. White, MD


Depigmented skin has lost all the pigment. Hypopigmented skin has lost only part of the pigment.

Congenital or Early in Life, Localized

Disease Comments
Nevus Depigmentosus Depigmented patch. Can be segmental.
Ash Leaf Macule Depigmented patch. Can be segmental. Look for other signs of tuberous sclerosis, (e.g., facial angiofibromas, periungual tumors, Shagreen patch)
Segmental Pigmentation Disorder Lesions are segmental, but not dermatomal and do not follow Blaschko's lines.
Hypomelanosis of Ito Bizarre whorled areas of depigmentation along Blaschko's lines
Piebaldism White forelock and normal pigmented skin in the hypopigmented areas
Waardenburg Syndrome White forelock, normal pigmented skin in the hypopigmented areas, increased interpupillary distance, deafness and heterochromic irides
Vitiligo Chalk white color. Completely depigmented. Commonly segmental, but if classic, will be progressive.
Nevus Anemicus Edge can be changed/blurred/removed by pressure. Is not accentuated with Wood's light.

Nevus Depigmentosus
Nevus Depigmentosus

Ash Leaf Macule in Tuberous Sclerosis
Ash Leaf Macule

Segmental Pigmentation Disorder
Segmental Pigmentation Disorder

Nevus Anemicus
Nevus Anemicus

Piebaldism
Piebaldism

Hypomelanosis of Ito
picture here

Congenital, Diffuse

Albinism

Acquired

A permanent white patch in an area of lichen simplex chronicus (after clearing with topical steroids) and constant scratching.
depigmentation

Pityriasis Alba
Pityriasis Alba

Progressive Macular Hypomelanosis
Progressive Macular Hypomelanosis

Cutaneous T-Cell Lymphoma

Chronic Graft Vs. Host Disease

Halo Nevus
Halo Nevus

Leprosy

Lichen Sclerosus
lichen sclerosus

Malignant Atrophic Papulosis
Malignant Atrophic Papulosis

Pinta

Postinflammatory Hypopigmentation
Postinflammatory Hypopigmentation

Sarcoidosis
Sarcoidosis

Segmental Vitiligo
Segmental Vitiligo

Scleroderma
Scleroderma

Steroid Injection
Hypopigmentation Following Steroid Injection

Tinea Versicolor
Tinea Versicolor

Vitiligo
Vitiligo

Melanoma-Associated Leukoderma
picture here

Vogt-Koyanagi-Harada Syndrome

Trichrome Vitiligo
Trichrome Vitiligo

White Lentiginosis Diffuse, scattered, acquired, lenticular, white macules in darker-skinned females, adult and children.

Acquired Depigmented Macules

Idiopathic Guttate Hypomelanosis

Melanoma-Associated Leukoderma
picture here

Vitiligo Ponctué

Punctate Leukoderma after Q switched laser therapy Ann Dermatol. 2017 Oct; 29(5): 630–632

Early vitiligo: A confetti-like pattern of depigmentation may be a harbinger of rapidly progressing vitiligo [JAAD 2015;73:272-5].

Idiopathic Confetti-like leukoderma [Am J Dermatopathol. 2012 Feb;34(1):117-21].

White Lentiginosis Familial often. Darker skinned patients. Usually women.

Rare

Vitiligo associated with Large Congenital Nevi. Depigmented patches may occur within large congenital nevi, adjacent to them, or distal [PD 2016;33;307].

RegionalDerm

Homepage | FAQs | Use of Images | Contact Dr. White


It is not the intention of RegionalDerm.com to provide specific medical advice, diagnosis or treatment. RegionalDerm.com only intends to provide users with information regarding various medical conditions for educational purposes and will not provide specific medical advice. Information on RegionalDerm.com is not intended as a substitute for seeking medical treatment and you should always seek the advice of a qualified healthcare provider for diagnosis and for answers to your individual questions. Information contained on RegionalDerm.com should never cause you to disregard professional medical advice or delay seeking treatment. If you live in the United States and believe you are having a medical emergency call 911 immediately.