By Gary M. White, MD
Flushing with Alcohol
Drugs: Many drugs may induce flushing including nicotinic acid, tamoxifen, bromocriptine and CSA. ASA blocks the nicotinic acid flush.
Mastocytosis Flushing in mastocytosis is mediated in part by histamine release. Look for hypotension, lacrimation, headache, stuffy nose, paresthesias, tachycardia, chest pain, and splenomegaly.
Medullary Carcinoma Of The Thyroid: MCT has been reported to cause a protracted flush of the face and upper extremities accompanied by discoloration and telangiectasias. Usually a mass is palpable on the neck and frequently metastases are evident before flushing develops.
Monosodium Glutamate: Monosodium glutamate ingestion may cause flushing--the so called Chinese restaurant syndrome.
Rosacea Flushing in rosacea is felt to occur by thermal induced flushing (see below).
Scromboid Fish Poisoning JAAD 2011;65;246.
Thermal Induced Flushing: Hot liquids such as coffee may induce flushing by heating the internal jugular vein, which by counter current, would heat the blood in the carotid artery, thus heating the anterior hypothalamus (the body's thermostat) leading to heat dissipating mechanisms including flushing.
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