PRIMARY MUCINOUS CARCINOMA OF THE SKIN
By Gary M. White, MD
Primary Mucinous Carcinoma Of The Skin (PMCS) is a tumor of the sweat glands, usually eccrine.
- The median age of onset is 60 years.
- The lesions is locally aggressive and recurrence rates are high.
- Lymph node metastasis occasionally occurs but widespread metastases are rare.
- A primary malignancy of the breast (e.g. mucinous breast carcinoma) or gastrointestinal tract with metastasis to the skin should be excluded.
A bluish, pink or red nodule of the upper or lower eyelid is characteristic. It may be firm, indurated or cystic. Lesions are most common on the head and neck but may occur elsewhere.
Positron emission tomography–computed tomography can be useful in the early detection of metastases in primary mucinous carcinoma of the skin on the head and neck [BJD 2015;173; 1263–1265].
Wide excision is appropriate.
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