POROKERATOTIC ECCRINE OSTIAL AND DERMAL DUCT NEVUS
By Gary M. White, MD
Linear lesion on the side of the foot of a teenager.
The porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is a rare nevoid condition characterized by asymptomatic grouped papules and plaques, often linear, of keratotic papules and comedone-like pits.
- The PEODDN usually presents at birth or in childhood.
- The palm is most commonly affected, followed by the sole.
- This mosaic epidermal disorder is often linear following lines of Blaschko.
- Association with KID syndrome has been reported.
- Mutations in the GJB2 gene have been associated with both conditions [JAMA Derm 2015;151;638].
Surgical excision may be considered for small and localized lesions in appropriate anatomical locations. CO2 laser was found to be effective in a few cases.
Close up. There was a corn that was pared in the lesion.
A 7-year-old girl presented with multiple asymptomatic keratotic papules over her right palm since 6 months of age. Dermatology Online Journal 18(1)
A 23-year-old otherwise-healthy young man presented with multiple elevated skin lesions on his left upper extremity and upper chest for five years. Indian Dermatol Online J. 2015 Mar-Apr; 6(2): 117–119
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