- Phrynoderma (meaning toad skin) seems to be a multifactorial disease without any one associated nutritional deficiency.
- No one deficiency has been found. Those most commonly considered are Vitamin A, Vitamin B complex, Vitamin E, and essential fatty acids (EFA) deficiency, as well as protein-calorie malnutrition.
- It seems to involve multiple nutrients, local factors like pressure and friction, and environmental factors in the setting of increased nutritional demand.
- Children, 5-15 years of age, are most commonly affected.
Discrete brown to skin-colored keratotic, follicular papules with a central keratinous plug are characteristic. The elbows, extensor side extremities, and buttocks are most common. The changes are usually bilateral, symmetric, and usually asymptomatic. Occasionally there is a mild itch.
A study from South India had showed that the intramuscular injection of Vitamin A/Vitamin B complex are effective in the treatment of phrynoderma [Therapeutic response of Vitamin A, Vitamin B complex, essential fatty acids (EFA) and Vitamin E in the treatment of phrynoderma: A randomized controlled study. J Clin Diagn Res 2014;8:116-8]. In another, the combination therapy with Vitamin A and B along with EFA (Safflower oil) supplementation showed the better results when compared with Vitamin A or B monotherapy [Indian J Paediatr Dermatol 2016;17:108-11].
Indian J Dermatol 2011;56:389-92
Homepage | FAQs | Contact Dr. White
It is not the intention of RegionalDerm.com to provide specific medical advice, diagnosis or treatment. RegionalDerm.com only intends to provide users with information regarding various medical conditions for educational purposes and will not provide specific medical advice. Information on RegionalDerm.com is not intended as a substitute for seeking medical treatment and you should always seek the advice of a qualified healthcare provider for diagnosis and for answers to your individual questions. Information contained on RegionalDerm.com should never cause you to disregard professional medical advice or delay seeking treatment. If you live in the United States and believe you are having a medical emergency call 911 immediately.