Multiple myeloma (MM) is a cancer formed by malignant plasma cells. A single plasma cell tumor is called an isolated (or solitary) plasmacytoma. When there are multiple plasmacytomas, the patient is said to have multiple myeloma. In the vast majority of cases, the malignant plasma cells remain in the bone marrow and their proliferation leads to deficiency in the production of normal blood components (e.g., anemia, leukopenia) and the development of lytic bone lesions. Only very rarely (< 1%) do the malignant cells invade the skin.


The most common patterns in the skin are papules, nodules, and plaques. They tend to be pink-red to violaceous. Ulceration may occur. Large lesions, up to 23 cm, have been reported [JAAD 2016;74;878].


Treatment by an oncologist is in order.


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