Morbihan disease is a rare condition in which there is persistent erythema and solid edema of the upper two thirds of the face. It is thought to be a late-stage complication of rosacea. Its etiology is poorly understood.
There is persistent erythema and edema of the upper two thirds of the face.
In one study, 5 patients were treated with isotretinoin with good results. Each patient required at least 6 months of treatment until any substantial clinical improvement was seen. The average dose was 60 mg/day and average treatment duration, 10-24 months.
Three men benefited from the administration of a diuretic--furosemide (60 mg/d) in two cases and spironolactone (75 mg twice daily) for a third patient [Ann Dermatol Venereol. 2012;139:559-63].
Another patient cleared after 4 months of minocycline 100/day [Acta Dermato-Venereologica 2015;95;368].
Dermatology Online Journal 18(12)
Acta Dermato-Venereologica 2015;95;368]
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