By Gary M. White, MD

Monosymptomatic hypochondriasis (MH) is a term applied to the manifestation of a single prominent belief that one is diseased in some particular way despite evidence to the contrary. Although MH may assume a variety of clinical forms, three consistently described syndromes are found in the literature:

These syndromes may be the clinical expression of a number of underlying pathologic conditions, including psychiatric disorders, structural brain disease, metabolic and endocrine disease, and toxic states.


Treatment needs to be individualized to each patient. Psychological evaluation is best, but may be resisted by the patient. See individual entries above for more treatment suggestions.


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