MELANOMA WITH REGRESSION
By Gary M. White, MD
Melanoma showing regression in the center.
Regression in melanoma occurs when the body's immune response attacks the primary tumor, destroying part or all of it. Often, a fibrotic component is left behind.
- 10-35% of melanoma show partial regression.
- Rarely, melanomas may fully regress [J Clin Aesthet Dermatol 2016;9;42].
- The majority of recognized fully regressed melanomas are associated with metastases.
A recent review found that regression is actually a positive prognostic sign and that SLNB should not be done in the absence of other additional risk factors [JEADV 2016;30;2030].
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