MELANOMA-ASSOCIATED LEUKODERMA (VITILIGO)

By Gary M. White, MD

Melanoma associated vitiligo These white patches appeared 4 months after diagnosis of this woman's melanoma.


Melanoma-associated leukoderma (MAL) is the concurrent development of vitiligo-like lesions along with melanoma.

Clinical

The most common pattern was multiple, round, patchy, confetti-like depigmented macules measuring 4-5 mm scattered symmetrically on the trunk, extremities, and/or face.

Treatment

Treatment of the melanoma is paramount. If an adult presents with "vitiligo" with this pattern, a complete search for melanoma should be undertaken. In the above series, the MAL was resistant to topical steroids and UVB phototherapy.

Additional Pictures

Same woman as above. MAV appearing in a woman 4 months after diagnosis of the melanoma.
Melanoma associated vitiligo Melanoma associated vitiligo Melanoma associated vitiligo Melanoma associated vitiligo

A man with MAV.

Melanoma associated vitiligo Melanoma associated vitiligo

Melanoma associated vitiligo

References

A 53-year-old woman presented with well-defined white patches distributed on the cheeks, chin, neck, and sternal area for four months. A complete examination disclosed a melanoma on her right leg. [Dermatology Online Journal 17(1)]

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