By Gary M. White, MD

The oral melanoacathoma (OM) is a rare, benign pigmented lesion of the oral mucosa, most commonly the buccal mucosa..


A rapidly growing solitary brown patch on the oral mucosa is typical. Multiple lesions may occur. Black women are most commonly affected.


Whereas in the normal epithelium the melanocytes are restricted to the basal layer, in the oral melanoacanthoma, melanocytes are dispersed throughout the epithelium.


No treatment is needed. Spontaneous regression may occur. The argon laser has been used.


Figure 1 of Dent Clin North Am. 2013 Oct; 57(4): 699–710.

Biopsy-proven oral melanoacanthoma of the hard palate. BMC Res Notes. 2013; 6: 30


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