MEDALLION-LIKE DERMAL DENDROCYTE HAMARTOMA
By Gary M. White, MD
Medallion-Like Dermal Dendrocyte Hamartoma (MLDDH) is a rare, congenital lesion in the shape of a medallion and is caused by the presence of dermal dendrocytes.
- MLDDH is also known as plaque-like CD34-positive dermal fibroma.
- This spindle cell proliferation, positive for CD34 and factor XIIIa resembles DFSP histologically.
The solitary, asymptomatic, congenital lesion is typically round, oval or triangular in shape, several centimeters in diameter, brown or erythematous in color, with well-defined borders, and with a slightly atrophic wrinkled surface. Biopsy with immunostaining allows diagnosis of this rare benign lesion. Rarely, lesions may be acquired or be factor XIIIa–negative.
No treatment is needed. Surgical excision, if feasible, may be done.
A 20-year-old man with a congenital, asymptomatic plaque on the anterior aspect of his neck. Dermatology Online Journal 17 (9)
Homepage | FAQs | Use of Images | Contact Dr. White
It is not the intention of RegionalDerm.com to provide specific medical advice, diagnosis or treatment. RegionalDerm.com only intends to provide users with information regarding various medical conditions for educational purposes and will not provide specific medical advice. Information on RegionalDerm.com is not intended as a substitute for seeking medical treatment and you should always seek the advice of a qualified healthcare provider for diagnosis and for answers to your individual questions. Information contained on RegionalDerm.com should never cause you to disregard professional medical advice or delay seeking treatment. If you live in the United States and believe you are having a medical emergency call 911 immediately.