By Gary M. White, MD

malignant pyoderma

It is unclear whether malignant pyoderma is a separate entity or a variant of pyoderma gangrenosum. Some of these cases have been identified as as an atypical form of Granulomatosis with Polyangiitis [J Eur Acad Dermatol Venereol. 2009;23:1008–17].


Rapidly developing crusted, ulcerating lesions affecting the head and neck of young people is typical.

Differential Diagnosis

A biopsy with cultures should be done (infection?). An ANCA should be drawn to exclude Granulomatosis with Polyangiitis. Is there any cocaine use? (levamisole vasculitis).

Additional Pictures

malignant pyoderma malignant pyoderma


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