By Gary M. White, MD

Mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome is a very rare disease in which the patient fulfills criteria for both Behcet's Syndrome and relapsing polychondritis.


Corticosteroids, dapsone and infliximab may be used for both disorders. Individual treatments for each disease may be done as well. See Behcet's Syndrome and relapsing polychondritis for more details.


A 40-year-old man had presented with arthralgia of the knees, ankles, and wrists; recurrent oral and genital ulcers; papulopustular lesions on the upper limbs and upper front torso, and painful nodules on the lower limbs. The diagnosis of Behçet's disease was made and he was well controlled with dapsone and other medications. Fourteen years after the onset of Behcet's Syndrome, he began recurrent crises of edema, erythema, and painful nodules on the ear auricles, more accentuated on the left side, which abated after increased corticosteroid treatment. An Bras Dermatol. 2014 Jan-Feb; 89(1): 177–17


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