Lymphocytoma cutis, aka pseudolymphoma

Lymphocytoma cutis (aka pseudolymphoma) is a dermal collection of lymphocytes and other inflammatory cells. The key initial intervention is to exclude malignancy, e.g. leukemia or lymphoma cutis. There are reports of lymphocytoma cutis eventuating into a B-cell lymphoma. In some cases, particularly in Europe, Borrelia has been associated. Various drugs have been reported to stimulate lesions that mimic lymphoma, so called drug-induced pseudolymphoma. See also pseudolymphoma of the lip.


A 0.5 -2 cm, asymptomatic, erythematous to plum-colored papule or nodule is characteristic. They may occur virtually anywhere with a special predilection for the ear lobes. A miliary type occurs. A skin biopsy, CBC and lymph node exam are reasonable to help exclude malignancy.


Therapy need not be done, as spontaneous resolution may occur. If desired, intralesional triamcinolone (e.g. 5-10 mg/cc) is usually quite effective and should be first line therapy. Cryotherapy has also been used.

Additional Pictures

Lymphocytoma cutis, aka pseudolymphoma Lymphocytoma cutis, aka pseudolymphoma Lymphocytoma cutis, aka pseudolymphoma Lymphocytoma cutis, aka pseudolymphoma


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