LIPODYSTROPHIA CENTRIFUGALIS ABDOMINALIS INFANTILIS

By Gary M. White, MD

Lipoatrophy centrifigus abdominalis Courtesy O. Dale Collins MD


Lipoatrophy centrifigus abdominalis is (LCA) is a rare lipoatrophy that occurs on the abdomen. For a related atrophy in childhood that follows Blaschko's lines, see linear atrophoderma of Moulin.

Clinical

A spreading, depressed, atrophic lesion with prominent vasculature and an erythematous border on the abdomen secondary to loss of fat is characteristic of LCA. The vast majority of patients are children with the onset occurring in the first five years of life. Approximately 80% appear initially in the groin and 20% in the axilla, followed by extension to the lower abdomen and/or chest.

One case was associated with a partial IgA deficiency, antinuclear antibodies and IgG antibodies against gliandin [BJD 1999;140;1161].

One follow-up study of 86 patients showed that the extension stopped at the onset of puberty. Thereafter the condition improved in most patients with some showing a complete recovery.

Treatment

Topical or oral steroids may be tried. As noted above, approximately 1/2 of cases resolve spontaneously.

Additional Pictures

Here in an adult.
Lipoatrophy centrifigus abdominalis Lipoatrophy centrifigus abdominalis

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