By Gary M. White, MD
Lipoatrophic panniculitis is a relatively poorly-described, rare panniculitis of mainly of children
A child with bouts of erythematous nodules that expand leaving a depressed lipoatrophic center is characteristic. The legs, thighs or arms are most commonly affected. Fever, malaise, abdominal pain, arthralgias and hepatosplenomegaly are often associated. There may be a preceding URI.
Histopathology shows a lobular panniculitis without vasculitis and with a mixed infiltrate.
Prednisone, methotrexate and dapsone have been used.
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