By Gary M. White, MD

Iododerma results from a hypersensitivity to iodides. Cases have occurred after orally or IV administered contrast dye and after oral potassium iodide. Decreased renal function and thus clearance of the iodine seems to be a factor in several cases.


The patient experiences the acute onset of tender pustules and nodules which enlarge to form crusted, vegetating plaques most commonly affecting the face. Individual lesions have been described as vesicular, pustular, hemorrhagic, urticarial, fungating, suppurative, or ulcerative. The areas of involvement seem to correspond to skin with the highest concentration of sebaceous glands.


Avoidance of the allergen is critical. Oral steroids, cyclosporin, and hemodialysis have been given.


Iododerma secondary to Sitz baths six to seven times per day containing 5–10 mL of 10% povidone iodine. [Australasian J Derm 2007 May; 48;102].

Acute iododerma secondary to iodinated contrast media [Br J Dermatol. 2014 Jun;170(6):1377-9].


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