By Gary M. White, MD

blood clot in skin This subcutaneous blood clot attached to a vessel is the classic location for IPEH.

Intravascular papillary endothelial hyperplasia (IPEH), also known as Masson tumor, is a benign, reactive lesion which is diagnosed histologically. Papillary or tuft-like proliferations of reactive endothelial cells are seen.


It usually presents as a firm, blue-black, dermal or subcutaneous nodule. Occasionally, nodules appear red, mimicking a hemangioma or pyogenic granuloma. It is usually < 2 cm in diameter and red, blue or even black in color. It may be tender or asymptomatic. It commonly occurs on the fingers, head and neck of a middle-aged adult.


Surgical excision both establishes the diagnosis and removes the lesion. Recurrence may occur, especially if there is an associated underlying vascular lesion.

Additional Pictures

blood clot in skin blood clot in skin


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