By Gary M. White, MD

imiquimod reaction on the ear This ear is inflamed from the treatment of AKs with 5% Imiquimod.

Caution: Facts about drugs changes frequently. The latest research, package insert and FDA information should be consulted before prescribing.


Side effects

External Genital Warts

Patient instructions


For external genital/perianal warts, Aldara is to be applied three days a week (e.g. MWF) for up to 16 weeks.

Actinic Keratoses


Dosing for AKs is twice weekly for 16 weeks.

Superficial Basal Cell Carcinoma

The target tumor should be a biopsy-proven superficial BCC, have a maximum diameter of no more than 2 cm and be located on the trunk (excluding anogenital skin), neck, or extremities (excluding hands and feet).


For superficial basal cell carcinomas, Aldara is to be applied once daily for five consecutive days per week for 6 weeks. Sufficient cream should be applied to cover the tumor and one centimeter of skin surrounding the tumor. Treatment should continue for 6 weeks unless your doctor tells you otherwise.


Aldara is supplied in single use tubes which are sufficient to cover 20 cm2.

Pregnancy Category C


Note that a few recent reports have recommended imiquimod for both basal cell carcinoma and Bowen's Disease.

Cutaneous T Cell Lymphoma

Treatment of AKs with imiquimod had induced changes of the skin which histologically mimic CTCL [JAMA Derm 2014;150;1236]

Additional Pictures

imiquimod reaction on the trunk


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