HIDRADENOMA PAPILLIFERUM

By Gary M. White, MD

Hidradenoma Papilliferum of the vulva


The hidradenoma papilliferum (HP) is a benign adnexal tumor of apocrine gland origin.

Clinical

A solitary dermal papule or nodule in the vulvar or perineal area is characteristic. Most are less than 1 cm in diameter. The color is pink or skin-colored in the majority, but some are blue. The surface is smooth in the majority, but some are ulcerated, umbilicated, or have a nipple-like morphology [JAAD 2016;75;380].

HP occurs most commonly in the genital area of women. When occurring outside the apocrine areas of the groin, axilla, and umbilicus, it has been called an ectopic HP. These are very rare and half of ectopic cases occur in men. An associated intraductal carcinoma of the mammary-type has been described. Other types of malignant change may rarely occur.

Treatment

Simple excision is appropriate.

Additional Pictures

Hidradenoma Papilliferum in the scalp
An ectopic HP on the scalp.

References

Hidradenoma papilliferum of the vulva. Indian Dermatol Online J 2014;5:523-4

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