By Gary M. White, MD

Hidradenoma Papilliferum of the vulva

The hidradenoma papilliferum (HP) is a benign adnexal tumor of apocrine gland origin.


A solitary dermal papule or nodule in the vulvar or perineal area is characteristic. Most are less than 1 cm in diameter. The color is pink or skin-colored in the majority, but some are blue. The surface is smooth in the majority, but some are ulcerated, umbilicated, or have a nipple-like morphology [JAAD 2016;75;380].

HP occurs most commonly in the genital area of women. When occurring outside the apocrine areas of the groin, axilla, and umbilicus, it has been called an ectopic HP. These are very rare and half of ectopic cases occur in men. An associated intraductal carcinoma of the mammary-type has been described. Other types of malignant change may rarely occur.


Simple excision is appropriate.

Additional Pictures

Hidradenoma Papilliferum in the scalp
An ectopic HP on the scalp.


Hidradenoma papilliferum of the vulva. Indian Dermatol Online J 2014;5:523-4


Homepage | FAQs | Use of Images | Contact Dr. White

It is not the intention of RegionalDerm.com to provide specific medical advice, diagnosis or treatment. RegionalDerm.com only intends to provide users with information regarding various medical conditions for educational purposes and will not provide specific medical advice. Information on RegionalDerm.com is not intended as a substitute for seeking medical treatment and you should always seek the advice of a qualified healthcare provider for diagnosis and for answers to your individual questions. Information contained on RegionalDerm.com should never cause you to disregard professional medical advice or delay seeking treatment. If you live in the United States and believe you are having a medical emergency call 911 immediately.