By Gary M. White, MD

Hemochromatosis The palm is normal and the back, bronzed.

Hemochromatosis is characterized by iron overload of the body. It may occur primarily in an inherited form or secondary form, e.g., excessive iron supplementation or blood transfusion.


The skin can become diffusely hyperpigmented or take on a bronze appearance from both hemosiderin deposition and increased production of melanin by the skin. It is most common on the sun-exposed areas, e.g., face, dorsal hands, and forearms. It may also affect the inguinal area.


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