GIANOTTI-CROSTI SYNDROME

By Gary M. White, MD

Gianotti-Crosti syndrome


Papular acrodermatitis of childhood (PAC), also known as Gianotti-Crosti syndrome, is a self-limited disorder with acute onset generalized lymphadenopathy and a symmetric erythematous papular and papulovesicular eruption of the face, neck, buttocks, and extremities, usually occurring in young children. This rash seems to result from an underlying viral infection, and has been noted to occur in association with molluscum, hepatitis B, varicella, coxsackie virus, CMV, enterovirus, hepatitis A, herpes simplex 1 virus and Epstein-Barr viruses.

Clinical

The patient presents with symmetric, inflammatory red papules and plaques on the arms, legs, and cheeks. It tends to spare the trunk.

Treatment

LFT's may be obtained but are usually normal. The rash will resolve within 4-6 weeks without sequelae.

Additional Pictures

An infant with PAC.
Gianotti-Crosti syndrome Gianotti-Crosti syndrome

A 5-year-old boy with 10 days of a rash prominent on the cheeks, knees and dorsal feet.
Gianotti-Crosti syndrome Gianotti-Crosti syndrome

Koebnerization may occur.
Gianotti-Crosti syndrome

RegionalDerm

Homepage | FAQs | Use of Images | Contact Dr. White


It is not the intention of RegionalDerm.com to provide specific medical advice, diagnosis or treatment. RegionalDerm.com only intends to provide users with information regarding various medical conditions for educational purposes and will not provide specific medical advice. Information on RegionalDerm.com is not intended as a substitute for seeking medical treatment and you should always seek the advice of a qualified healthcare provider for diagnosis and for answers to your individual questions. Information contained on RegionalDerm.com should never cause you to disregard professional medical advice or delay seeking treatment. If you live in the United States and believe you are having a medical emergency call 911 immediately.