GENERALIZED ERUPTIVE HISTIOCYTOSIS

By Gary M. White, MD


Generalize eruptive histiocytosis (GEH) is a rare non-Langerhans cell histiocytosis that presents with multiple nodules.

Clinical

The typical patient presents with multiple asymptomatic red to brown macules and papulonodules on the trunk and extremities.

Treatment

Since the disease may remit spontaneously, observation may be done. Other approaches include the carbon dioxide laser, cryotherapy, PUVA, hydroxychloroquine, oral isotretinoin and systemic steroids.

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