FREY'S SYNDROME

In Frey's syndrome, there is excessive sweating, flushing or both localized to the distribution of the auriculotemporal nerve in response to gustatory stimuli. It is not an uncommon sequel to traumatic lesions of the auriculotemporal nerve. It is thought that sympathetically denervated sweat glands are reinnervated by aberrant parasympathetic fibers. In adults, it may follow parotid surgery. In infants, it often affects those who were delivered with forceps. Herpes Zoster has precipitated Frey's syndrome (see reference below).

Clinical

Excessive flushing, sweating or both of the cheek during is seen. It may manifest itself during infancy with the introduction of solid food, and has been misdiagnosed as food allergy in this setting.

Treatment

In infants treatment is ineffective and unnecessary. This benign condition often resolves spontaneously. For adults, injection of botulinum toxin is first line treatment [JEADV 2016;30;907]. Topical application of anticholinergic drugs has also been done.

References

  1. A 14-month-old boy with recurrent episodes of facial flushing, each of which lasted for a few minutes, began when the patient was 6 months old and were always triggered by chewing solid foods. CMAJ. 2013 Apr 2; 185(6): 504

RegionalDerm

Homepage | FAQs | Contact Dr. White


It is not the intention of RegionalDerm.com to provide specific medical advice, diagnosis or treatment. RegionalDerm.com only intends to provide users with information regarding various medical conditions for educational purposes and will not provide specific medical advice. Information on RegionalDerm.com is not intended as a substitute for seeking medical treatment and you should always seek the advice of a qualified healthcare provider for diagnosis and for answers to your individual questions. Information contained on RegionalDerm.com should never cause you to disregard professional medical advice or delay seeking treatment. If you live in the United States and believe you are having a medical emergency call 911 immediately.