By Gary M. White, MD

Fournier's gangrene is a life-threatening necrotizing fasciitis of the perineum and genital area.


The rapid onset of erythema and necrosis of the scrotum caused by a polymicrobial infection occurs in Fournier's synergistic gangrene.


This potentially very serious infection should be treated with hospitalization, IV antibiotics, and debridement of any devitalized tissue. Early treatment with systemic steroids and IV antibiotics has been advocated.


A 46-year-old man with uncontrolled type 2 diabetes and alcoholic liver disease presented with painful swelling in the scrotum and perianal region. The physical examination was notable for necrotic-appearing tissue in the scrotum and perineum, with areas of induration and crepitus. N Engl J Med 2017; 376:1158


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