FIBROUS HAMARTOMA OF INFANCY

By Gary M. White, MD

Fibrous hamartoma of infancy Note the rectangular red area on flank of this infant. Palpation showed a firm dermal plaque (see photo below).


Fibrous hamartoma of infancy (FHI) is a benign soft tissue tumor that usually appears during the first 2 years of life. It is usually solitary with no associated syndromes. There is a male predominance. Children are usually healthy.

Clinical

FHI may present as solitary or multiple firm skin nodules, plaques, or masses. They may be localized to the dermis or subcutaneous tissue. Approximately 20% of cases are present at birth and 90% in the first year of life. They may occur nearly anywhere including back, legs, scrotum, and arms. Possible surface changes include hyperpigmentation, hypertrichosis, and hyperhidrosis. Diagnosis is done with a skin biopsy.

Treatment

Complete local excision of the tumor is curative. It usually does not recur, even if excision is not complete. Whether or not lesions may spontaneously resolve is yet unknown.

Additional Pictures

Fibrous hamartoma of infancy Fibrous hamartoma of infancy

References

A baby girl with a sacral plaque with localized hypertrichosis and perspiration. Ped Derm 2015;32;533–535

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