By Gary M. White, MD

Favre-Racouchot syndrome Multiple cysts and comedones about the eyes.

Favre-Racouchot syndrome (FRS) is the presence of comedones (blackheads and whiteheads) in the sun-exposed areas (usually the temples/cheeks) of an elderly person.


Cysts and comedones about the lateral eyes and cheeks in a middle-aged to elderly patient with a significant history of sun exposure is characteristic. The comedones may occur in groups. A rare case of large bilateral nodules has been reported.


Any patients who smoke should stop. Sun protection to prevent further disease is to be recommended. No treatment is needed. Adapalene or tretinoin QHS may be tried.

I personally have found lidocaine followed by curettage of the cysts and comedones followed by healing through secondary intention to be very effective and giving good cosmetic results.

Daily oral Isotretinoin (0.05-0.1 mg/kg/day) used in conjunction with topical tretinoin has also been recommended [Int J Dermatol. 2004 Mar;43(3):167-9].


A two-step treatment of CO2 laser resurfacing and manual pressure-induced expression of comedones was reported as an effective and durable treatment for FRS with an excellent cosmetic outcome [BJD March 2014].

Additional Pictures

Favre-Racouchot syndrome Favre-Racouchot syndrome


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