By Gary M. White, MD

Familial dyskeratotic comedones (FDC) is a rare autosomal dominant condition.


Clinically one sees numerous, discrete, disseminate, hyperkeratotic papules, and comedones. There is a predilection for the trunk, arms, legs, face and shaft of the penis (sparing the glans), oral mucosa, palms, and soles. Onset is usually in adolescence, but can present as dark papules even at a younger age.


Treatment is difficult. Topical retinoids and oral isotretinoin have proved ineffective. Frequent sun exposure and carbon dioxide laser have been recommended.


Familial dyskeratotic comedones: A rare entity. Indian Dermatol Online J 2016;7:46-8


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