By Gary M. White, MD

Eruptive hypomelanosis is a newly described entity characterized by diffuse hypomelanotic lesions occurring in a child. It is thought to represent a viral exanthem. The term paraviral is used to indicate that the disease is suspected to be caused by viruses, but a single virus-exanthem relationship has not been universally accepted. Other paraviral exanthems include pityriasis rosea.


Three is a prodrome of coryzal symptoms, eruption of successive crops of hypopigmented lesions without erythema. They have been described as macular lesions 3 to 8 mm in diameter with fairly distinct margins. The patients tend to be 2-9 years of age.

One child who was biopsied 3 days after onset of the rash showed slight orthohyperkeratosis, slight epidermal spongiosis, and nonspecific upper dermal patchy inflammatory lymphocytic infiltrates [JAMA Derm 2014;150;1197].


There is spontaneous recovery in 2–4 weeks.


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