By Gary M. White, MD
Epidermolysis Bullosa Pruriginosa (EBP) is a rare subtype of dystrophic epidermolysis bullosa (DEB) characterized by intense pruritus, nodular or lichenoid lesions, and violaceous linear scarring, most prominently on the extensor extremities, especially the shins.
Initially, erosions and bulla may be seen. Later, lichenified papules and linear plaques from scratching develop. The lesions may be very pruritic. Bulla and lichenoid violaceous papules may be occur together on the anterior aspects of the lower legs. DIF is negative. There may be scattered lesions elsewhere. The nails may be dystrophic.
The typical therapy as provided for EB patients is needed. See epidermolysis bullosa. The pruritus may be treated with topical and intralesional steroids. Skin grafts have occasionally been needed.
A 12-year-old girl with low IQ with intense pruritic lesions on the leg for the past 10 years.
Pretibial dystrophic epidermolysis bullosa pruriginosa: A rare case report in a child with low intelligent quotient. Indian J Paediatr Dermatol 2016;17:32-4
Pretibial epidermolysis bullosa Dermatology Online Journal 14(10)
Lichen amyloidosis was coexistent in his case. Indian J Dermatol Venereol Leprol 2015;81:40-2
Indian Dermatol Online J. 2014 Jan-Mar; 5(1): 44–47
Homepage | FAQs | Contact Dr. White